Search results for " TIMP-2"

showing 3 items of 3 documents

Gelatinases and their tissue inhibitors in a group of subjects with obstructive sleep apnea syndrome.

2016

Obstructive sleep apnea syndrome (OSAS) is associated with an elevated risk of cardiovascular events and stroke. Matrix metalloproteinases (MMPs) are endopeptidases involved in extracellular matrix degradation and then in the development and progression of cardiovascular diseases. Our aim was to evaluate plasma levels of gelatinases (MMP-2 and MMP-9) and their tissue inhibitors (TIMP-1 and TIMP-2) in a group of subjects with OSAS. We enrolled 48 subjects (36 men and 12 women; mean age 49.7 ± 14.68 yrs) with OSAS diagnosed with a 1-night cardiorespiratory study and then we subdivided these subjects into two subgroups according to the apnea/hypopnea index (AHI): Low (L = 21 subjects with AHI …

Malemedicine.medical_specialtyGelatinasesSettore MED/09 - Medicina InternaPhysiologyMMP-2; MMP-9; obstructive sleep apnea; TIMP-1; TIMP-2; Disease Progression; Female; Gelatinases; Humans; Male; Middle Aged; Sleep Apnea Obstructive; Tissue Inhibitor of Metalloproteinase-1; Physiology; Hematology; Cardiology and Cardiovascular Medicine; Physiology (medical)030204 cardiovascular system & hematologyMatrix metalloproteinaseGastroenterologyTIMP-203 medical and health sciencesTIMP-10302 clinical medicinePhysiology (medical)Internal medicinemedicineHumansStrokeobstructive sleep apneaOxygen saturation (medicine)Sleep Apnea ObstructiveTissue Inhibitor of Metalloproteinase-1MMP-2business.industryApneaCardiorespiratory fitnessHematologyMiddle Agedmedicine.diseasenervous system diseasesrespiratory tract diseasesObstructive sleep apneaEndocrinology030228 respiratory systemGelatinaseGelatinasesDisease ProgressionFemalemedicine.symptomMMP-9Settore MED/36 - Diagnostica Per Immagini E RadioterapiaCardiology and Cardiovascular MedicinebusinessHypopneaHumanClinical hemorheology and microcirculation
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Gli aneurismi dell'aorta addominale

2009

Not available

Settore BIO/17 - IstologiaAbdominal aortic aneurism ACE IL MMPs PAF TIMP-2 atherosclerosis EVARSettore MED/22 - Chirurgia VascolareAneurisma aorta addominale ACE IL MMPs PAF EVAR
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Behaviour of the plasma concentration of gelatinases and their tissue inhibitors in subjects with venous leg ulcers.

2015

Venous leg ulcers are common in subjects with chronic venous insufficiency. The increased intraluminal pressure causes alteration of the skin microcirculation, leukocyte activation and release of proteolytic enzymes leading to ulceration. An impaired expression and activity of matrix metalloproteases (MMPs) and their tissue inhibitors (TIMPs) might influence extracellular matrix degradation and deposition in chronic venous ulcers with the failure of the healing process. Our aim was to evaluate plasma concentration of gelatinases (MMP-2 and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in subjects with venous leg ulcers before and after the compression therapy. We enrolled 36 subjects (12 …

Ulcer healingMalemedicine.medical_specialtyGelatinasesSettore MED/09 - Medicina InternaPhysiologyChronic venous insufficiencyMatrix metalloproteinaseGastroenterologyMicrocirculationVaricose UlcerTIMP-2TIMP-1Physiology (medical)Internal medicinemedicineHumansAgedTissue Inhibitor of Metalloproteinase-2Tissue Inhibitor of Metalloproteinase-1MMP-2business.industryMMP-2; MMP-9; TIMP-1; TIMP-2; Venous leg ulcersLeg UlcerProteolytic enzymesHematologyVenous bloodmedicine.diseaseMatrix MetalloproteinasesSurgeryVenous leg ulcersVenous InsufficiencyGelatinasesPlasma concentrationMatrix Metalloproteinase 2FemaleMMP-9Cardiology and Cardiovascular Medicinebusiness
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